Colostrum for SIBO and Endometriosis: Powerful Gut Connection

colostrum for SIBO and endometriosis

This post aims to draw connections from the latest research on the microbiome, and here we will discuss the research on colostrum for SIBO, gut health, and immune functioning including potential upstream benefits for those with endometriosis.

Disclaimer: This is not intended to be medical advice. For medical advice, please seek the help of a qualified medical professional. If this post contains outbound links, as an Amazon Affiliate, I may earn on qualifying purchases.

What is Colostrum?

Colostrum is the first milk produced by mammals that have just given birth and are post-partum. It is a thicker and more nutrient dense substance than the recognizable milk that comes afterwards and there have been many studies investigating its compounds and seeking insight into its benefits for applications in human nutrition.

Colostrum is composed of proteins, fats, glycans, minerals and vitamins, peptides, ash, hormones, growth factors, cytokines, nucleotides and less lactose than mature milk.

Colostrum has been used culturally and regionally for both animal and human consumption. More recently, European cultures utilize colostrum in its cheeses and other traditional foods. It is also available dried as a supplement with boasts of benefits for immune system support and gastrointestinal wellness.

Bioactive Compounds in Colostrum: Intestinal Support Formula

Research into colostrum and cultural and regional use have highlighted benefits of colostrum for the development of the gastrointestinal tract.

Colostrum intake shapes the development and function of the microbiome and impacts both the metabolic and endocrine systems of baby calves. It can help the muscular-skeletal system with growth and repair, assists with proper immune system function and may be helpful with viral and bacterial infections.

The body of research also implicates a transfer of benefit for human consumption of colostrum. Clinical studies suggest that bovine colostrum products are well-tolerated, nontoxic and safe for human ingestion.

Colostrum is considered a complete protein, as it contains all of the amino acids and high protein digestibility.

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The Colostrum and SIBO Connection

The growth factors, antimicrobial and immunoregulatory activities make colostrum an interesting subject for those looking to assist with small intestinal bacterial overgrowth, or, SIBO.

SIBO is as the name implies, when the small intestine contains bad actors, namely microbes that should not be present. These microbes can include Streptococcus, Escherichia coli, Staphylococcus, Bacteroides, Klebsiella, Enterococcus and Proteus or Salmonella. These microbes can hinder the absorption of nutrients in the small intestine and hinder the immune system 80% of which is found in the small intestine. It can also cause gut permeability leading to a condition commonly referred to as “leaky gut” where molecules enter the blood stream instead of staying within the gastrointestinal tract.

A recent 2021 research study found that when using bovine colostrum and egg helped to strengthen the mucosal integrity of the small intestine against the types of bacteria relevant in SIBO.

Further, in human trials, there is substantial evidence of the efficacy of bovine colostrum in inflammatory disorders, bowel disease and infectious diarrhea due to this ability to heal the mucosal lining.

Finally, it has shown to be effective at reducing vaginal dryness, as a prevention against upper respiratory infection, and as a modulator of the immune system response in sick and healthy people. Additional research is needed to study this further.

Links Between SIBO and Endometriosis

Research shows there is a link between SIBO and endometriosis. While there are tests on the market that can help with giving a definitive answer as to whether you test positive or not, many practitioners find symptomology to be a strong indicator of the condition. (And, sometimes the test may be false positives or incorrectly negative, so there’s that).

Symptoms include bloating after eating, bloating just because, constipation, diarrhea, both constipation and diarrhea, stronger incidence of food allergies or allergies in general and tenderness in the lower abdomen.

Though, you don’t need to have active symptoms to have SIBO.

Many women have these gut microbiome issues and many women with endometriosis are more likely than the average population to have SIBO, IBS or IBD.

Having a compromised gut, as I mentioned, can disrupt your immune system causing immune system dysregulation, it can lead to your food not being absorbed as needed nutrients, causing nutrient deficiency, and it can lead to host of auto-immune conditions because of the permeable gut leaking food-toxins into the blood stream that the immune system targets forever and becomes either over-reactive or exhausted and under-reacts.

Perhaps the colostrum leaky gut helper is worth considering further as bovine colostrum reduces leaky gut per the research literature.

Incorporating Colostrum into Your Wellness Routine

Is a colostrum product right for you? It may be worth investigating further.

Personal Testimonials and Experiences

Aside from the research literature and human clinical trials, those who have used used colostrum share about its benefits to their lives.

There are 1,000s of happy customers on Amazon who have been using colostrum supplements for quite some time. Some of the reasons users report using colostrum supplements is as follows:

  • Improved gut health, especially after antibiotics
  • For auto-immune conditions
  • For skin conditions, such as eczema or to add health to the skin
  • For immune regulation
  • For athletic performance
  • For feelings of strength, vitality and increased energy
  • Wonderful, natural source of protein for general body repair

Consultation with Healthcare Providers

As with any dietary supplement, caution is advised. Do your due diligence regarding the sourcing and quality of any supplement your purchase and speak with your doctor about any supplements you may add for medical advice.


For those looking for natural remedies and food as medicine, colostrum may be a consideration given its benefits for so many modern-day common ailments. For those with more severe gut issues and co-occurring diseases such as endometriosis it may be worth paying special attention.

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